Upgrade automatizace krystalizace
9 600 000 9,6 milionů Kč
Zadavatel
Biotechnologický ústav AV ČR, v. v. i.
Dodavatel
Podání nabídek
Datum zveřejnění
17. července 2025
Popis
Předmětem plnění veřejné zakázky je dodávka, instalace a zprovoznění upgrade automatizace krystalizace spolu se službami, jež se vztahují k předmětu dodávky dle specifikace uvedené v Návrhu kupní smlouvy.
Jedná se o upgrade:
i) Krystalizačního robota NT8 výrobce Formulatrix, Inc. (HW) a
ii) SW Formulatrix prostředí (základními složkami jsou RockImager, RockMaker a RockMakerWeb), který se
týká přístrojů výrobce Formulatrix, Inc.:
Krystalizační hotel RI1000 (vč. SW RockImager, RockMaker a RockMakerWeb a tiskárny čárových kódů)
(pořizovací cena: 3.955.120,- Kč bez DPH, r. 2015; navýšení kapacity hotelu v r. 2019 v hodnotě 82 006 EUR bez DPH)
SONICC (pořizovací cena: 678.808 EUR, r. 2021)
Krystalizační hotel RI182 (pořizovací cena 249 785 EUR, r. 2020)
Krystalizační robot NT8 (pořizovací cena: 106 392 EUR bez DPH, r. 2019)
Absolutní (minimální) technické požadavky / Absolute (minimum) technical requirements:
Upgrade of Nanodispenzer for protein crystallization experiments,
• Nanodispenzer must have an automatic calibration option, which can calibrate the system without the necessity to use the manual mode.
• Nanodispenser must be able to dispense nanoliter drops with range of at least 50-200 nl.
• Nanodispenser must be able to do the sitting drop and hanging drop crystallization experiments, including 96-well plates of SBS format and 24-well plates
• Must include Plate Copy option, to be able to dispense/pipette well solutions from at least 96-well deep well blocks to 96-well crystallization plates
• Must be able to dispense lipidic cubic phase experiments
• The dispenser must be able to control the humidity around the small drops to avoid the evaporation. Must be able to set relative humidity from ambient up to 95 % and actively keep that level.
• Dispenser must be able to re-use tips when user choses to do so, but also be able to use disposable tips to avoid contamination in certain pipetting experiment.
• The upgraded plate copy option must avoid the need to lubricate the large-volume pipetting head o-rings;
• Must run on Windows 11
Upgrade to the Formulatrix Environment/Software Upgrade
• All new versions of software must be compatible with the existing crystallography equipment including RI1000 with SONICC, RI182, the barcode printer and the upgraded version of NT8.
• Upgrade will allow remote access from various operating systems -at least Windows, Mac, Linux (not including mobile phones)
• Upgrade to browser-based software, meaning the software is not reliant on a specific Windows version. The possibility to use the on-site application will be kept as well.
• Addition of crystallisation autoscoring models including MARCO, Sherlock 1 and Sherlock 2
• Updated search and filter to allow quick comparison of drop images to better understand crystal growth parameters
• Enhanced crystal tracking for synchrotron trips allowing for reusability of dewars and pucks in different trips
• Full installation must be provided
• Full training on new software must be included
• Must run on Windows 11
• Rock Maker Web upgrade must be also included, and must continue to provide remote user access at least as per the current software configuration Noví dodavatelé 🤏 Zadavatel má pouze 41 % nových dodavatelů
Toto info je pouze po
registrované
uživatele.
Jedná se o upgrade:
i) Krystalizačního robota NT8 výrobce Formulatrix, Inc. (HW) a
ii) SW Formulatrix prostředí (základními složkami jsou RockImager, RockMaker a RockMakerWeb), který se
týká přístrojů výrobce Formulatrix, Inc.:
Krystalizační hotel RI1000 (vč. SW RockImager, RockMaker a RockMakerWeb a tiskárny čárových kódů)
(pořizovací cena: 3.955.120,- Kč bez DPH, r. 2015; navýšení kapacity hotelu v r. 2019 v hodnotě 82 006 EUR bez DPH)
SONICC (pořizovací cena: 678.808 EUR, r. 2021)
Krystalizační hotel RI182 (pořizovací cena 249 785 EUR, r. 2020)
Krystalizační robot NT8 (pořizovací cena: 106 392 EUR bez DPH, r. 2019)
Absolutní (minimální) technické požadavky / Absolute (minimum) technical requirements:
Upgrade of Nanodispenzer for protein crystallization experiments,
• Nanodispenzer must have an automatic calibration option, which can calibrate the system without the necessity to use the manual mode.
• Nanodispenser must be able to dispense nanoliter drops with range of at least 50-200 nl.
• Nanodispenser must be able to do the sitting drop and hanging drop crystallization experiments, including 96-well plates of SBS format and 24-well plates
• Must include Plate Copy option, to be able to dispense/pipette well solutions from at least 96-well deep well blocks to 96-well crystallization plates
• Must be able to dispense lipidic cubic phase experiments
• The dispenser must be able to control the humidity around the small drops to avoid the evaporation. Must be able to set relative humidity from ambient up to 95 % and actively keep that level.
• Dispenser must be able to re-use tips when user choses to do so, but also be able to use disposable tips to avoid contamination in certain pipetting experiment.
• The upgraded plate copy option must avoid the need to lubricate the large-volume pipetting head o-rings;
• Must run on Windows 11
Upgrade to the Formulatrix Environment/Software Upgrade
• All new versions of software must be compatible with the existing crystallography equipment including RI1000 with SONICC, RI182, the barcode printer and the upgraded version of NT8.
• Upgrade will allow remote access from various operating systems -at least Windows, Mac, Linux (not including mobile phones)
• Upgrade to browser-based software, meaning the software is not reliant on a specific Windows version. The possibility to use the on-site application will be kept as well.
• Addition of crystallisation autoscoring models including MARCO, Sherlock 1 and Sherlock 2
• Updated search and filter to allow quick comparison of drop images to better understand crystal growth parameters
• Enhanced crystal tracking for synchrotron trips allowing for reusability of dewars and pucks in different trips
• Full installation must be provided
• Full training on new software must be included
• Must run on Windows 11
• Rock Maker Web upgrade must be also included, and must continue to provide remote user access at least as per the current software configuration Noví dodavatelé 🤏 Zadavatel má pouze 41 % nových dodavatelů
Dřívější dodavatelé
Odkaz na zdroj
Toto info je pouze po
registrované
uživatele.
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